Machine Learning & Soft Computing Techniques

Paper Code: 
BIF 325 B
12.00
Unit I: 
Machine Learning Foundations & Algorithms

The Probabilistic Framework Bayesian Modeling, The Cox-Jaynes Axioms, Probabilistic Modeling and Inference Dynamic Programming, Gradient Descent, EM/GEM Algorithms, Markov Chain Monte Carlo Methods, Simulated Annealing, Evolutionary and Genetic Algorithms, Learning Algorithms

10.00
Unit II: 
Neural Networks

Theory- Introduction, Universal Approximation Properties, Priors and Likelihoods, Learning Algorithms: Back propagation, Application in Bioinformatics, SNNS tool.

14.00
Unit III: 
Hidden Markov Models & hybrid system

Introduction, Prior Information and Initialization, Likelihood and Basic Algorithms, Learning Algorithms, Advantages and Limitations of HMMs. Applications in Bioinformatics, HMMer tool. Hybrid Systems: HMM & Neural Networks - Introduction to Hybrid Models, The Single-Model Case, The Multiple-Model Case, Simulation Results

13.00
Unit IV: 
Genetic Algorithm & Fuzzy methods

Genetic Operators and Parameters, Theoretical Foundations of Genetic Algorithms, Implementation issues, Application in Bioinformatics Introduction to Fuzzy Sets, Operations on Fuzzy sets, Fuzzy Relations, Fuzzy Measures, Applications in Bioinformatics

11.00
Unit V: 
Support Vector Machines

The Learning Methodology, Linear Methods, Kernels, Feature Spaces, Generalization & Optimization Theory, Implementation, Applications in Bioinformatics, SVM lite tool.

ESSENTIAL READINGS: 

1. Pierre Baldi and S Brunak. Bioinformatics: The Machine Learning Approach. MIT Press. 2001 2. Goldberg DE. Genetic Algorithms in Search, Optimization, and Machine Learning, Addison-Wesley. 1989 3. Sinha NK & Gupta MM. (Eds). Soft Computing & Intelligent Systems: Theory & Applications, Academic Press. 2000 4. Mitchell M. An Introduction to Genetic Algorithms, Prentice-Hall. 1998

REFERENCES: 

1. D.W. Patterson, “Introduction to AI and Expert Systems”, PHI, 1992. 2. E. Rich and K. Knight, “Artificial Intelligence”, Tata Mc Graw Hill, 2nd ed., 1992. 3. G.J. Klir and B. Yuan. Fuzzy Sets and Fuzzy Logic: Theory and Applications, Prentice-Hall. 1995 4. Freeman, J. and Skapura, D., Neural Networks: Algorithms, Applications, and Programming Techniques, Addison-Wesley. 1991

Academic Year: