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Fermentation Technology
Paper Code:
AMB 501
Credits:
03
Contact Hours:
45
Objective:
This paper will enable students to:
- Learn the industrial aspects of microbiology and the basic approach towards fermentation.
- Understand downstream processing and product recovery
- Understand the role of microorganisms in industrial production of different products.
- Have a basic idea of nanotechnology.
8.00
Unit I:
Bioreactors
The fermentation industry, screening of industrially important microorganisms.
Factors involved in Bioreactor design, design of a bioreactor, Types of Bioreactors.
8.00
Unit II:
Fermentation Process
Types of fermentation- batch, continuous, fed batch, surface, and submerged and solid state fermentation.
Inoculum development, media formulation, scale-up. Process control.
9.00
Unit III:
Down Stream Processing and Product Recovery
Filtration, centrifugation, cell disruption, solvent extraction, precipitation, chromatography (gel filtration, ion exchange, affinity) membrane processes (ultra filtration) and spray drying.
11.00
Unit IV:
Industrial Products Derived from Microorganisms
Antibiotic- Penicillin. Steroids, Vaccines. Production of organic acid- Acetic acid, Citric acid, Production of amino acids- Glutamic acid, Industrial alcohol and SCP and Mushroom cultivation
9.00
Unit V:
Enzymes
Production of enzymes- Protease, amylase, lipase.
Methods of immobilization of enzymes and applications of enzyme immobilization.
Biosensors. Nanotechnology.
ESSENTIAL READINGS:
1. Industrial Microbiology, E Casida, New Age International (P) Ltd. Publishers. 2005
2. Manual of Industrial Microbiology and Biotechnology, A L Demain and J E Davies, ASM Press, 1999
3. Principles of Fermentation Technology, 2nd edition, P F Stanbory, Whitaker and Hall, Elsevier India, 2005
REFERENCES:
1. A Textbook of Industrial Microbiology, 2nd edition, W Crueger and A Crueger, Panima Publication Corporation, 2000
2. Fermentation Microbiology and Biotechnology, Mansi and Bryce, Taylor & Francis group, 2002
3. Industrial Microbiology, 4th edition, S C Prescott and D C Dunn, CBS Publishers and Distributors, 1987
4. Nanobiotechnology: Concepts, Applications & Perspectives, C N Niemeyer and
C A Mirkin, Wiley-VCH Verlag GmbH & Co., 2004
5. Process Biotechnology Fundamentals, 2nd edition, S N Mukhopadhyaay, Viva books Pvt. Ltd., 2004
Academic Year:
