Advance Paper-I Paper III: Toxicology

Paper Code:

25LSC143B

Credits:

Contact Hours:

UNITS	TOPICS	TEACHING HOURS
Unit I	History and scope of Toxicology Environmental Toxicology Economic Toxicology Forensic Toxicology Different areas of Toxicology Classification of Toxic Agents	10
Unit II	Disposition of Toxicants Absorption, Distribution & Excretion of Toxicants Mechanisms of Toxicity Delivery Absorption Distribution Excretion Cellular Dysfunctions and resultant toxicities Repair or Dysrepair Biotransformation of Xenobiotics Phase I Enzymes (Hydrolysis, Reduction, Oxidation Phase II Enzyme Reactions (Glucuronidation, Sulfation, Methylation, Acelylation, Amino-acid conjugation Glutathione Conjugation, Phosphorylation )	15
Unit III	Target Organ Toxicity Liver Blood Physicochemical nature & Effect of Toxic Agents Pesticides Metals Bioaccumulation and Biomagnification of Toxicants	15
Unit IV	Non-Organ-Directed Toxicity Chemical Carcinogenesis Genetic Toxicology	10
Unit V	Environmental Toxicology Air Pollution Ecotoxicology: Chemodynamics, Biomarkers, Terrestrial and Aquatic Ecotoxicology	10

ESSENTIAL READINGS:

· Casarett and Daull’s Toxicology: The basic science of poisons. By: Curtis D. Klaassen 6^th Edn., McGraw-Hill (Medical Publishing Div. NewYork

· Environmental Biotechnology – by. Indu Shekhar Thakur, I.K. International Pub.(2006)

· Toxicology, Principles and Applications: Raymond I.M.. CRC Publication.

· Microbial Ecology: Fundamentals and Applications by Atlas Bartha (An imprint of Addison Wesley Longman Inc)

· Environmental Microbiology: Maier R.M., Academic Press. 2000 Press, Cambridge. 1993.

· Environmental Science- A global concern; Cunningham W.P. and Saigo B.W Win. C. Brown Publishers, London, 1995.

· Advances in Industrial Waste Water Treatment; P.K. Goel; Technoscience Publications. Jaipur, 1999.

· An Introduction to Air Pollution; Trivedy R.K. and Goel P.K., Technoscience Publications, Jaipur, 1995.

· Problems of Environment Management in India; Goel M.M., Sharma M.C. and Purohit N.K; Anupriya Publishing House, Jaipur, 1999.

· Environmental Science (A study of interrelations); Enger E.D. and Smith B.F.; Win. C. Brown Pub. (Latest Edition).

· Botkin D. And Keller E. Environmental Science. Earth as a Living Planet; Botkin D. And Keller E

Academic Year:

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