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UNITS
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TOPICS
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TEACHING HOURS
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Unit I
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Teratogenesis
- General principle of teratology (genetic factors, critical period, initiating mechanism, consequences of abnormal development, Access to embryo and fetus- dose response relationship)
- Teratological mechanism (mutation, chromosomal abnormalities, mitotic interference, interference with nucleic acid function, nutritional deficiencies , altered energy, changes in osmolarity, changes in cell membrane, enzyme inhibition.)
- Teratogens; some specific examples.(Human and experimental animals)
- Transport and biotransformation of xenobiotics by placenta/extra embryonic membranes.
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15
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Unit II
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Reproductive Toxicology
- Female reproduction (Hypothalamus, ovary assessment of female reproductive functions),
- Male reproduction (Biology of male reproduction, assessment of male reproductive function)
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Unit III
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Embryogenesis of Chick
- Reproduction
- Structure and chemistry of the fertilized egg
- Cleavage
- Blastulation
- Gastrulation
- Neurulation and tubulation
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10
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Unit IV
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Development of chick according to the hours of incubation
- 25hrs
- 33 hrs
- 48 hrs
- 72 hrs
- 96 hrs till hatching.
- Extra embryonic membranes of chick-types and their development
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10
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Unit V
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Avian Teratology:
- Acute Oral Toxicity Studies
- Dietary Toxicity Studies
- Endocrine Disruptor Studies
- Embryotoxicity of Industrial Chemical on chick embryo
- Physiological and Biological effects of pesticide residues in poultry
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15
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