The objectives of this course are to cover all essentials required to appreciate physico-chemical principles underlying biological processes.
Course Outcomes (COs):
Course |
Course Outcomes |
Learning and teaching strategies |
Assessment Strategies |
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Course Code |
Course Title |
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24BTE127 |
Basics of Chemistry and Physics (Theory)
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CO37: Understand the fundamental laws and principle involved in motion, properties of matter, collisions and waves CO38: Understand the basic laws of thermodynamics CO39: Predict physical and chemical characteristics of elements in various groups and periods according to ionic size, charge, etc. and describe various types of hybridization and geometry of molecules. CO40: Appraise the rules of kinetics to evaluate the order of reaction and rate constant. CO41: Acquire in-depth knowledge of states of matter, redox reactions, Newman projections CO42: Contribute effectively in course-specific interaction
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Approach in teaching: Interactive Lectures, Demonstrations, Power point presentations Learning activities for the students: Discussion, Tutorials, Assignments, Reading journals |
Class test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Presentation, Individual and group projects |
Physical quantities and their dynamics: definitions and dimensions; vectors & scalars, displacement, velocity, acceleration, kinematic formulas, angular momentum, torque etc. force, power, work, energy (kinetic & potential/electric charge separation, electromagnetic spectrum, photons etc.); springs & Hookes laws; elastic and inelastic collisions; Newton’s law of motions (centripetal and centrifugal forces etc.); simple harmonic motions, mechanical waves, Doppler effect, wave interference, amplitude, period, frequency & wavelength
Diffusion, dissipation, random walks, and directed motions in biological systems; low Reynolds number - world of Biology, buoyant forces, Bernoulli’s equation, viscosity, turbulence, surface tension, adhesion; laws of thermodynamics: Maxwell Boltzmann distribution, conduction, convection and radiation, internal energy, entropy, temperature and free energy, Maxwell’s demon (entropic forces at work in biology, chemical assemblies, self-assembled systems, role of ATP); Coulomb’s law, conductors and insulators, electric potential energy of charges, nerve impulses, Ohms law (basic electrical quantities: current, voltage & power), electrolyte conductivity, capacitors and capacitance, dielectrics; various machines in biology i.e. enzymes, allostery and molecular motors (molecules to cells and organisms).
Basic constituents of matter - elements, atoms, isotopes, atomic weights, atomic numbers, electronic configuration of atoms, basics of mass spectrometry, molecules, Avogadro number, molarity, gas constant, molecular weights, structural and molecular formulae, ions and polyatomic ions; chemical bonds (ionic, covalent, Van der Walls forces); electronegativity, polarity; VSEPR theory and molecular geometry, dipole moment, orbital hybridizations, Magnetism-Para magnetism and diamagnetism
chemical reactions, reaction stoichiometry, rates of reaction, rate constants, order of reactions, Arrhenious equation, Maxwell Boltzmann distributions, rate-determining steps, catalysis, chemical thermodynamics - internal energy, heat and temperature, enthalpy (bond enthalpy and reaction enthalpy), entropy, Gibbs free energy of ATP driven reactions, spontaneity versus driven reactions in biology; kinetic versus thermodynamic controls of a reaction, reaction equilibrium (equilibrium constant)
states of matter - vapor pressure, phase diagrams, surface tension, boiling and melting points, solubility, capillary action, suspensions, colloids and solutions; acids, bases and pH - Arrhenious theory, pH, ionic product of water, weak acids and bases, conjugate acid-base pairs, buffers and buffering action etc; redox reactions and electrochemistry - oxidation-reduction reactions, standard cell potentials, Nernst equation, resting membrane potentials, bond rotations and molecular conformations - Newman projections, conformational analysis of alkanes, alkenes and alkynes; functional groups, optically asymmetric carbon centers
● Elements of Mechanics”, J.C. Upadhyaya ,Himalaya Publishing House,2006
● Fundamental University Physics, Vol I and II , M.Alonso & J.Finn, Addisson Wiesley.
● Statistical and Thermal Physics, S. Loknathan and R.S. Gambhir, Prentice Hall, New Delhi 1991
● A Text Book of Physical Chemistry, Second Edition; A.S. Negi, S.C. Anand; New Age International (P) Ltd., New Delhi, 2007.
● Principles of Physical Chemistry, Forty Eighth Edtion; B.R. Puri, L.R. Sharma, M. S. Pathania; Vishal Publishing Co., Jalandhar, India, 2020.
● Organic Chemistry, Sixth Edition; R. T. Morrison, R. N. Boyd; Pearson Education India, New Delhi, 2017.
● Stereochemistry: Conformation and Mechanism, Tenth Edition; P.S. Kalsi; New Age International Publishers Pvt. Ltd., New Delhi, 201
● Concise Inorganic Chemistry, Fifth Edition; J.D. Lee; Wiley India(P) Ltd, New Delhi, 2008.
Principles of Inorganic Chemistry, Thirty Third Edition; B.R. Puri, L.R. Sharma, K.C. Sharma; Vishal Publishing Co., Delhi, 2020.