FERMENTATION TECHNOLOGY

Paper Code: 
MBL 501
Credits: 
03
Contact Hours: 
45
Objective: 

This paper will enable students to:

  • Learn the industrial aspects of microbiology and the basic approach towards fermentation.

  • Understand downstream processing and product recovery

  • Understand the role of microorganisms in industrial production of different products.

  • Have a basic idea of nanotechnology

                                                             

                                                             

8.00
Unit I: 
Bioreactors

The fermentation industry, screening of industrially important microorganisms.

Factors involved in Bioreactor design, design of a bioreactor, CSTR, Fluidized bed bioreactor

8.00
Unit II: 
Fermentation Process

Modes of fermentation- batch, fed batch, continuous. Inoculum development, media formulation and sterilization, Process control parameters (temperature, pH and DO)

 

Unit III: 
Industrial Products Derived from Microorganisms

Antibiotic- Penicillin. Production of organic acid- Acetic acid, Production of amino acids- Glutamic acid, Industrial alcohol, SCP and Mushroom cultivation.

9.00
Unit IV: 
Down Stream Processing and Product Recovery

Filtration, centrifugation, cell disruption, solvent extraction, precipitation, chromatography (gel filtration, ion exchange, affinity) membrane processes (ultra filtration) and spray drying.

9.00
Unit V: 
Enzymes

Production of enzymes- Protease, amylase, lipase.

Methods of immobilization of enzymes and applications of enzyme immobilization.

ESSENTIAL READINGS: 
  1. Industrial Microbiology, E Casida, New Age International (P) Ltd. Publishers. 2005
  2. Manual of Industrial Microbiology and Biotechnology, A L Demain and J E Davies, ASM Press, 1999
  3. Principles of Fermentation Technology, 2nd edition, P F Stanbory, Whitaker and Hall, Elsevier India, 2005
REFERENCES: 
  1. A Textbook of Industrial Microbiology, 2nd edition, W Crueger and A Crueger, Panima Publication Corporation, 2000
  2. Fermentation Microbiology and Biotechnology, Mansi and Bryce, Taylor & Francis group, 2002
  3. Industrial Microbiology, 4th edition, S C Prescott and D C Dunn, CBS Publishers and Distributors, 1987
  4. Nanobiotechnology: Concepts, Applications & Perspectives, C N Niemeyer and
  5. C A Mirkin, Wiley-VCH Verlag GmbH & Co., 2004
  6. Process Biotechnology Fundamentals, 2nd edition, S N Mukhopadhyaay, Viva books Pvt. Ltd., 2004
Academic Year: 
2019-2020
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