Genetics

Paper Code: 
BTE 301
Credits: 
3
Contact Hours: 
45
Objective: 

This paper will enable students to-

  • learn the basics of Genetics and its importance in biological systems
  • study sex linked inheritance in plant and animals
  • learn the basics of linkage and bacterial recombination
  • learn the basics of mutation and its effect on evolution and health
  • study the fundamentals of population genetics
9.00
Unit I: 
Mendelian genetics

Mendelian genetics-Mendel’s Experiment and Laws of inheritance, Gene interactions-co dominance and incomplete dominance Epistasis (recessive and dominant), Complementary and Supplementary genes, Lethal genes.

 

9.00
Unit II: 
Sex determination & sex linked inheritance

Sex determination mechanisms in plants and animals. Non-disjunction theory and Genetic balance theory, Sex chromatin bodies and Dosage compensation, Sex linked inheritance.

9.00
Unit III: 
Linkage, Recombination & Genetic system

Spontaneous and induced mutations, types of point mutations, physical and chemical mutagens. Structural and numerical chromosomal aberrations.

Evolution of wheat, cotton and Raphanobrassica.  Hereditary defects in humans-Downs syndrome, Klinfelters syndrome and Turners syndrome.

10.00
Unit IV: 
Mutations

Spontaneous and induced mutations, types of point mutations, physical and chemical mutagens. Structural and numerical chromosomal aberrations.

Evolution of wheat, cotton and Raphanobrassica.  Hereditary defects in humans-Downs syndrome, Klinfelters syndrome and Turners syndrome.

8.00
Unit V: 
Extra chromosomal inheritance & population genetics

Extra chromosomal inheritance, maternal effect, chloroplast and mitochondrial genetic system.

Population genetics-gene and genotype frequency, Hardy-Weinberg equilibrium.

ESSENTIAL READINGS: 
  1. Gene IX, Lewin, Oxford university Press, 2007
  2. Microbial Genetics, 2nd edition, Maloy, D Freidfelder and John E  Cronan., Jones and Barlett Publishers, 1994
  3. Principles of Genetics, 8th edition, E J Gardener, M J Simmons and D P Snustad, John Wiley and Sons Publications, 2005
REFERENCES: 
  1. Advanced Genetics, G S Miglani,  Narosa Publication House, 2003
  2. Cell Biology & Molecular Biology, 8th edition, E D P Roberties and E M F Roberties, Lippincott Williams and Wilkins, 2005
  3. Fundamental Genetics, J Ringo, Cambridge University Press, 2004
  4. Genetics, 3rd edition, M V Strickberger, Prentice Hall of India Pvt. Ltd.,
Academic Year: 
2019-2020
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