Genetics

Paper Code: 
BTE 301
Credits: 
03
Contact Hours: 
45
Objective: 

This course will enable the students to -

 

  1. learn the basics of Genetics and its importance in biological systems
  2. study sex linked inheritance in plant and animals
  3. learn the basics of linkage and bacterial recombination
  4. learn the basics of mutation and its effect on evolution and health
  5. study the fundamentals of population genetics

 

Course Outcomes (COs):

 

Course

Learning outcome (at course level)

Learning and

teaching strategies

Assessment Strategies

Paper Code

Paper Title

 

 

 

 

 

 

 

 

 

BTE 301

 

 

 

 

 

 

 

 

 

Genetics

CO 29 study sex linked inheritance in plant and animals

 

CO 30 learn the basics of linkage and bacterial recombination

 

CO 31 Understand Process of DNA replication transcription, translation

 

CO 32 study the fundamentals of population genetics

 

CO 33 identification of genetic regulatory mechanism and distinguishing different mechanism of gene regulation

Approach in teaching: Interactive Lectures, Discussion, Tutorials, Reading assignments, presentations

 

Learning activities for the students: Self-learning assignments, Effective questions, Seminar presentation, Giving tasks.

C A test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Classroom interaction

 

 

CO 34 Understand molecular mechanism of mutations and

DNA repair

 

 

 

9.00
Unit I: 
Mendelian genetics
  • Mendelian genetics-Mendel’s Experiment and Laws of inheritance, Gene interactions-co dominance and incomplete dominance Epistasis (recessive and dominant), Complementary and Supplementary genes, Lethal genes.

 

9.00
Unit II: 
Sex determination & sex linked inheritance
  • Sex determination mechanisms in plants and animals. Non-disjunction theory and Genetic balance theory, Sex chromatin bodies and Dosage compensation, Sex linked inheritance.

 

 

9.00
Unit III: 
Linkage, Recombination & Genetic system
  • Linkage and mapping genes, CIS-TRANS or complementation test for functional allelism.
  • Recombination in bacteria-conjugation, transformation and transduction.

 

10.00
Unit IV: 
Mutations
  • Spontaneous and induced mutations, types of point mutations, physical and chemical mutagens. Structural and numerical chromosomal aberrations.
  • Evolution of wheat, cotton and Raphanobrassica.      Hereditary defects in humans-Downs syndrome, Klinfelters syndrome and Turners syndrome.

 

 

8.00
Unit V: 
Extra chromosomal inheritance & population genetics
  • Extra chromosomal inheritance, maternal effect, chloroplast and mitochondrial genetic system.
  • Population genetics-gene and genotype frequency, Hardy-Weinberg equilibrium.

 

 

ESSENTIAL READINGS: 
  • Gene IX, Lewin, Oxford university Press, 2007
  • Microbial Genetics, 2nd edition, Maloy, D Freidfelder and John E    Cronan., Jones and Barlett Publishers, 1994
  • Principles of Genetics, 8th edition, E J Gardener, M J Simmons and D P Snustad, John Wiley and Sons Publications, 2005
  • Advanced Genetics, G S Miglani, Narosa Publication House, 2003
  • Cell Biology & Molecular Biology, 8th edition, E D P Roberties and E M F Roberties, Lippincott Williams and Wilkins, 2005
  • Fundamental Genetics, J Ringo, Cambridge University Press, 2004
  • Genetics, 3rd edition, M V Strickberger, Prentice Hall of India Pvt. Ltd., 2004

 

Academic Year: 
2021-2022
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