Immunology

Paper Code: 
BTE 401
Credits: 
03
Contact Hours: 
45
Objective: 

This course will enable the students to –

 

  1.  learn the fundamentals of immune system
  2. study the various cellular and molecular aspects of immune system
  3. understand the regulation of immune response
  4. learn various immunological diagnostic techniques

Course Outcomes (COs): 

Course

Learning outcome (at course level)

Learning and teaching strategies

Assessment

Strategies

Paper Code

Paper Title

 

 

 

 

 

 

 

 

BTE 401

 

 

 

 

 

 

 

 

Immunology

CO 44 learn the fundamentals of immune system

CO 45 study the various cellular and molecular aspects of immune system

CO  46 understand the regulation of immune response

CO 47 Understand the role of different types of Cells, Effector Molecules and Effector Mechanisms in Immunology.

CO 48 Understand the principles underlying various Immunotechniques.

Approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, presentations

 

Learning activities for the students:

Self-learning assignments, Effective questions, Seminar presentation, Giving tasks.

 

C A test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Classroom interaction

 

 
8.00
Unit I: 
Basic Immunology

Introduction to immune system- Innate and acquired immunity. Cells of the Immune system: Hematopoiesis and differentiation, B-lymphocytes, T-lymphocytes, Macrophages, Dendritic cells, NK cells, Eosinophils, Neutrophils and Mast Cells. Structure and function of lymphoid organs

 

11.00
Unit II: 
Cellular and molecular aspects

Nature and biology of antigens and super antigens

Immunoglobulin: structure, types and their function

MHC, B and T-Cell Receptor

      Complement system

10.00
Unit III: 
Immune response & its regulation

Generation of Humoral and Cell mediated immune responses

B-and T- cell maturation, activation and differentiation

Cytokines and their role in immune regulation

T-cell regulation, MHC restriction

Immunological tolerance

7.00
Unit IV: 
Antigen- antibody interactions

Antigen processing and presentation, Precipitation, Immunodiffusion, Immunoelectrophoresis, Agglutination, RIA, ELISA, Immunofluorescence

9.00
Unit V: 
Selected concepts in Immunology

Hypersenstivity

Autoimmunity

Vaccine Types: RD vaccines, Peptides, Proteins, DNA

      AIDS and other immunodeficiencies (SCID, DiGeorge syndrome, Chediak- Higashi            syndrome)

ESSENTIAL READINGS: 
  1. Kuby Immunology, R.A. Goldsby and others, 4th edition, Freeman & Co., New York, 2001
  2. Roitt’s Essential Immunology, Ivan M .Roitt and Peter J. Delves, 10th edition, Blackwell Science, 2001
  3. Instant Notes on Immunology, Lydyard, Wheran and Fanger, 2nd edition, Viva Books Pvt. Ltd., 2003

 

REFERENCES: 
  1. Cellular and Molecular Immunology, Abbas, Litchman and Pober, 3rd edition, Harcourt Brace and Company, 1998
  2. Immunology: A Comprehensive, Darla J. Wise and Gordon R. Carter, Iowa State University Press, 2001
  3. Medical Microbiology and Immunology: Examination and Board Review by Warren Levinson and Ernst Jawetz, 7th edition, Mc Graw Hill, 2002

 

Academic Year: 
2020-2021
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