IMMUNOLOGY

Paper Code: 
BTE 401
Credits: 
03
Contact Hours: 
45
Objective: 

This course will enable the students to –

 

  1. learn the fundamentals of immune system
  2. study the various cellular and molecular aspects of immune system
  3. understand the regulation of immune response
  4. learn various immunological diagnostic techniques

 

Course Outcomes (COs):

 

Course

Learning outcome (at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

 

 

CO 44 learn the fundamentals of immune system

 

CO 45 study the various cellular and molecular aspects of immune system

Approach in teaching: Interactive Lectures, Discussion, Tutorials, Reading assignments, presentations

C A test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Classroom

interaction

 

 

 

 

 

BTE 401

 

 

 

 

 

Immunology

CO 46 understand the regulation of immune response

 

CO 47 Understand the role of different types of Cells, Effector Molecules and Effector Mechanisms in Immunology.

Learning activities for the students:

Self-learning assignments, Effective questions, Seminar presentation, Giving tasks.

 

 

 

CO 48 Understand the principles underlying various

Immunotechniques.

 

 

 

8.00
Unit I: 
Basic Immunology
  • Introduction to immune system- Innate and acquired immunity
  • Cells of the Immune system: Hematopoiesis and differentiation, B-lymphocytes, T-lymphocytes, Macrophages, Dendritic cells, NK cells, Eosinophils, Neutrophils and Mast Cells. Structure and function of lymphoid organs

 

11.00
Unit II: 
Cellular and molecular aspects
  • Nature and biology of antigens and super antigens
  • Immunoglobulin: structure, types and their function
  • MHC, B and T-Cell Receptor
  • Complement system

 

10.00
Unit III: 
Immune response & its regulation
  • Generation of Humoral and Cell mediated immune responses
  • B-and T- cell maturation, activation and differentiation
  • Cytokines and their role in immune regulation
  • T-cell regulation, MHC restriction
  • Immunological tolerance

 

7.00
Unit IV: 
Antigen- antibody interactions
  • Antigen processing and presentation
  • Precipitation,    Immunodiffusion,     Immunoelectrophoresis,     Agglutination,     RIA,    ELISA, Immunofluorescence

 

9.00
Unit V: 
Selected concepts in Immunology
  • Hypersenstivity
  • Autoimmunity
  • Vaccine Types: RD vaccines, Peptides, Proteins, DNA
  • AIDS and other immunodeficiencies (SCID, DiGeorge syndrome, Chediak- Higashi syndrome)

 

ESSENTIAL READINGS: 

      

 

  • Instant Notes on Immunology, Lydyard, Wheran and Fanger, 2nd edition, Viva Books Pvt. Ltd., 2003
  • Cellular and Molecular Immunology, Abbas, Litchman and Pober, 3rd edition, Harcourt Brace and Company, 1998
  • Immunology: A Comprehensive, Darla J. Wise and Gordon R. Carter, Iowa State University Press, 2001
  • Medical Microbiology and Immunology: Examination and Board Review by Warren Levinson and Ernst Jawetz, 7th edition, Mc Graw Hill, 2002. 
  • Roitt’s Essential Immunology, Ivan M .Roitt and Peter J. Delves, 10th edition, Blackwell Science, 2001
  • Kuby Immunology, R.A. Goldsby and others, 4th edition,      Freeman & Co., New York, 2001

 

 

 

Academic Year: 
2021-2022
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