Fermentation Technology

Paper Code: 
MBL 501
Credits: 
3
Contact Hours: 
45
Objective: 

·      Learn the industrial aspects of microbiology and the basic approach towards fermentation.

  • Understand downstream processing and product recovery
  • Understand the role of microorganisms in industrial production of different products.
  • Have a basic idea of nanotechnology
8.00
Unit I: 
Bioreactors

 

                                                                                                  

The fermentation industry, screening of industrially important microorganisms.

Factors involved in Bioreactor design, design of a bioreactor, CSTR, Fluidized bed bioreactor

 

8.00
Unit II: 
Fermentation Process

                                                                           

Modes of fermentation- batch, fed batch, continuous. Inoculum development, media formulation and sterilization, Process control parameters (temperature, pH and DO)

 

11.00
Unit III: 
Industrial Products Derived from Microorganisms

 

Antibiotic- Penicillin. Production of organic acid- Acetic acid, Production of amino acids- Glutamic acid, Industrial alcohol, SCP and Mushroom cultivation.

9.00
Unit IV: 
Down Stream Processing and Product Recovery

 

                                    

Filtration, centrifugation, cell disruption, solvent extraction, precipitation, chromatography (gel filtration, ion exchange, affinity) membrane processes (ultra filtration) and spray drying.

 

 

9.00
Unit V: 
Enzymes

                                                                                                                                            

Production of enzymes- Protease, amylase, lipase.

Methods of immobilization of enzymes and applications of enzyme immobilization.

ESSENTIAL READINGS: 

 

  1. Industrial Microbiology, E Casida, New Age International (P) Ltd. Publishers. 2005
  2. Manual of Industrial Microbiology and Biotechnology, A L Demain and J E Davies, ASM Press, 1999
  3. Principles of Fermentation Technology, 2nd edition, P F Stanbory, Whitaker and Hall, Elsevier India, 2005

 

 

 

 

1.    

REFERENCES: 

A Textbook of Industrial Microbiology, 2nd edition, W Crueger and A Crueger, Panima Publication Corporation, 2000

2.     Fermentation Microbiology and Biotechnology, Mansi and Bryce, Taylor & Francis group, 2002

3.     Industrial Microbiology, 4th edition, S C Prescott and D C Dunn, CBS Publishers and Distributors, 1987

4.     Nanobiotechnology: Concepts, Applications & Perspectives, C N Niemeyer and

5.     C A Mirkin, Wiley-VCH Verlag GmbH & Co., 2004

6.     Process Biotechnology Fundamentals, 2nd edition, S N Mukhopadhyaay, Viva books Pvt. Ltd., 2004

Academic Year: