MICROBIOLOGY

Paper Code: 
BTE 123
Credits: 
5
Contact Hours: 
75
Objective: 

Course Outcomes (COs):

               Course Outcomes

Learning and teaching strategies

Assessment Strategies

  
 

Upon completion of the course the learner will:

CO 12 : Examine the microbial evolution and assess various methods of chemotaxonomy

CO 13 : Summarize the structural characteristics of prokaryotes, microbial growth and nutritional classification 

CO 14: Assess the diversity of various prokaryotes

CO  15:  Assess the diversity of some eukaryotes and interpret the processes of chemolithotrophy

CO  16:  Analyze and interpret the process of host-parasite relationships, principles of epidemiology and Chemotherapy

Class lectures

Seminars

Tutorials

Group discussions and Workshops

Question preparation

Class test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Presentation, Individual and group projects

  

 

16.00
Unit I: 
Taxonomy
  • Microbial evolution, systematic and taxonomy-Evolution of earth and earliest life forms; primitive organisms, their metabolic strategies and molecular coding; approaches to bacterial taxonomy, DNA-DNA and DNA-RNA hybridization, G+C content determination, ribotyping, Ribosomal RNA sequencing; Characteristics of primary domains, Taxonomy, Nomenclature and Bergey's Manual. Culture collection, maintenance and preservation of microorganisms.

 

 

13.00
Unit II: 
Structural characteristics of Prokaryotes, Microbial growth and nutritional classification
  • Cell wall composition and synthesis. Flagella, Cilia and motility. Cell inclusions like Glycogen granules, Volutin granules, Carboxysomes etc, Endospores, Slime sheet and capsule.
  • Microbial Growth-The definition of growth, mathematical expression of growth, growth curve, measurement of growth and growth yields, Synchronous growth, Continuous, Batch and Fed Batch Culture; Growth as affected by environmental factors like temperature, acidity, alkalinity, water availability and oxygen; nutritional classification of microorganisms 

 

 

10.00
Unit III: 
Microbial Diversity – I
  • Bacteria: Photosynthetic bacteria (cyanobacteria, purple & green bacteria)
  • Budding bacteria, Spirochaetes, Sheathed bacteria, Endospore forming rods   and cocci, Mycobacteria, Rickettsias, Chlamydias and Mycoplasma,        Actinomycetes.

 

16.00
Unit IV: 
Microbial Diversity – II
  • Structure of archebacteria and eukaryotic cells.
  • Archaea: Archaea as earliest life forms; Halophiles, Methanogens;        Hyperthermophilic archaea and Thermo plasma,
  • Eukarya: Algae, Fungi, Slime molds and Protozoa.
  • Chemolithotrophy; Hydrogen, Iron, Nitrate and oxidizing bacteria; Nitrate and sulfate reduction; Syntrophy; Role of anoxic decomposition; Nitrogen fixation

 

20.00
Unit V: 
Host Parasite Relationships and Chemotherapy
  • Normal micro flora of skin, oral cavity, gastrointestinal tract. Anaerobic ecosystem- Rumen microbiology.
  • Entry of pathogens into the host; colonization and factors predisposing to infections; types of toxins (Exotoxin, Endotoxin and Enterotoxin) and their structure; mode of actions; virulence and pathogenesis
  • Disease reservoirs; Epidemiological terminologies; infectious disease transmission;
  • Emerging and resurgent infectious diseases (Tuberculosis chicken pox, AIDS, hepatitis Malaria)
  • Chemotherapy and Antimicrobial agents; Sulfa drugs; Antibiotics; Pencillins and Cephalosporins; Broad-Spectrum antibiotics; Antibiotics from prokaryotes; Antifungal antibiotics; Mode of action; Resistance to antibiotics.

 

 

ESSENTIAL READINGS: 

ESSENTIAL READINGS: 

  • Microbiology ,5th edition, M J Pelczar, E C S Chan, N R Kreig, Tata Mc Graw Publication, 2019
  • Microbiology-a Laboratory Manual, 10th edition, J G Cappuccino and N Sherman, Addison Wesley, Pearson Education, Inc., 2014
  • Microbiology-an introduction, 13th edition, G.J. Tortora, B.R. Funke, C.L. Case Pearson Education, Inc., 2020
  • Prescott’s Microbiology, 11th edition, J Willey, K Sandman, D Wood,  Mc Graw Hill Companies, 2019
  • General microbiology, 7th edition, H S Schlegel, Cambridge University Press, 1995
  • Microbial diversity: current perspectives and potential applications, Satynarayana T. &Johri B.N. I.K. International Pvt. Ltd. 2005
  • Microbiology: principles and explorations, 9th edition, J G Black, L J Black, John Wiley and Sons, Inc, 2015

SUGGESTED READINGS:

  • Advances in Microbial Physiology, 1st edition, R K Poole, Academic Press, 2006
  • Brock Biology of Microorganisms, 14th edition, M T Madigan, J M Martinko, K S Bender, D H Buckley, D A Stahl, Pearson Education, Inc., 2017
  • General Microbiology, 5th edition, R Y Stanier, J L Ingharam, M L Wheelies, P R Painter, Mac Millan Education Ltd, 1999
  • Fundamentals of microbiology, 11th edition, J C. Pommerville, Jones & Barlett Publishers, 2017
  • Foundation in Microbiology, 11th edition, K P Talaro and A Talaro, Mc Graw Hill, 2021

 

REFERENCES: 

e RESOURCES:

JOURNALS:

 

 

Academic Year: 
2022-2023
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