NANOBIOTECHNOLOGY

Paper Code: 
24MBL227B
Credits: 
02
Contact Hours: 
30
Objective: 

Course Objectives: The objectives of this course are to sensitize students about various types of nanomaterials and their applications. The students will apply the nano structures for various purposes and design strategies for better applications.

 

Course Outcomes (COs):

Course

 Course Outcomes

Learning and teaching strategies

Assessment Strategies

Course Code

Course Title

24MBL227B

 

Nanobiotechnology

(Theory)

 

CO85B: Analyze various types of nanomaterials and their applications, explain the synthesis and characterization of nanomaterials

CO86B: Design nano films and their characterization

CO87B: Apply the nano structures for various purposes and design strategies for better applications

CO88B: Develop nanobiocatalysts and nanoscaffolds for production of drug and their intermediates

CO89B: Identify toxicity of nanoparticles and devise methods to detect toxicity of nanoparticles

CO90B: Contribute effectively in course-specific interaction

Approach in teaching:  Interactive Lectures,

Demonstrations.

 

Learning activities for the students:  Discussion,

Tutorials,

Assignments

Reading Journals

Class test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Presentation, Individual and group projects

 

6.00
Unit I: 
Introduction to Nano biotechnology

Introduction to Nanobiotechnology; Concepts, historical perspective; Different formats of nanomaterials and applications with example for specific cases; Cellular Nanostructures; Nanopores; Biomolecular motors; Bio-inspired Nanostructures, Synthesis and characterization of different nanomaterials.

 

4.00
Unit II: 
Nano – films

Thin films; Colloidal nanostructures; Self Assembly, Nano vesicles; Nanospheres; Nanocapsules and their characterisation.

 

8.00
Unit III: 
Nano – particles and their Applications

Nanoparticles for drug delivery, concepts, optimization of nanoparticle properties for suitability of administration through various routes of delivery, advantages, strategies for cellular internalization and long circulation, strategies for enhanced permeation through various anatomical barriers.

Nanoparticles for diagnostics and imaging (theranostics); concepts of smart stimuli responsive nanoparticles, implications in cancer therapy, nanodevices for biosensor development.

6.00
Unit IV: 
Nano – materials

Nanomaterials for catalysis, development and characterization of nanobiocatalysts, application of nanoscaffolds in synthesis, applications of nanobiocatalysis in the production of drugs and drug intermediates.

 

6.00
Unit V: 
Nano – toxicity

Introduction to Safety of nanomaterials, Basics of nanotoxicity, Models and assays for Nanotoxicity assessment; Fate of nanomaterials in different stratas of environment; Ecotoxicity models and assays; Life Cycle Assessment, containment.

 

ESSENTIAL READINGS: 

ESSENTIAL READINGS

  • Gero Decher, Joseph B. Schlenoff, (2003); Multilayer Thin Films: Sequential Assembly of Nanocomposite Materials, Wiley-VCH Verlag GmbH & Co. KGaA
  • David S. Goodsell, (2004); Bionanotechnology: Lessons from Nature; Wiley-Liss
  • Neelina H. Malsch (2005), Biomedical Nanotechnology, CRC Press
  • Greg T. Hermanson, (2013); Bioconjugate Techniques, (3rd Edition); Elsevier
  • Recent review papers in the area of Nanomedicine.

SUGGESTED READING

  • Springer Handbook of Nanotechnology- Ed. by B. Bhushan, Springer-Verlag (2004)
  • Vacuum Technology, A. Roth, North- Holland Pub., 2nd Edition (1982)
  • The Chemistry of Nanomaterials: Synthesis, Properties and Applications, C.N.R. Rao, A. Muller, A. K. Cheetham (Eds), Wiley-VCH Verlag (2004)
  • B.S. Murty and S. Ranganathan, International Materials Reviews (1998) Vol. 43(3), 101. Introduction to nanoscience and nanotechnology, CRC Press, Tylor and Francis Group,
  • Boca Raton, G. L. Hornyak, H. F. Tibbals, J. Dutta and J J. Moore. Introductory Nanoscience: Physical and Chemical Concepts, CRC Press, Tylor and Francis Group,
  • Boca Raton, M. Kuno. Nanochemistry: A chemical approach to Nanomaterials Ozin and Arsenault Roayal Society of Chemistry, Cambridge, UK First Edition, 2005.

e RESOURCES

JOURNALS

  • IET Nano biotechnology, Wiley
  • Nanomaterials and Nanotechnology, SAGE Publication
  • Nano Materials Science, Science direct

 

 

 

 

Academic Year: 
2024-2025
  • Printer-friendly version
  • PDF version