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Semester III B.Sc. (Pass Course) - Biotechnology (2016-17)
This paper will enable students to- • learn the basics of Genetics and its importance in biological systems • study sex linked inheritance in plant and animals • learn the basics of linkage and bacterial recombination • learn the basics of mutation and its effect on evolution and health • study the fundamentals of population genetics
Mendelian genetics-Mendel’s Experiment and Laws of inheritance, Gene interactions-co dominance and incomplete dominance Epistasis (recessive and dominant), Complementary and Supplementary genes, Lethal genes
Sex determination mechanisms in plants and animals. Non-disjunction theory and Genetic balance theory, Sex chromatin bodies and Dosage compensation, Sex linked inheritance
Linkage and mapping genes, CIS-TRANS or complementation test for functional allelism. Recombination in bacteria-conjugation, transformation and transduction
Spontaneous and induced mutations, types of point mutations, physical and chemical mutagens. Structural and numerical chromosomal aberrations.
Evolution of wheat, cotton and Raphanobrassica. Hereditary defects in humans-Downs syndrome, Klinfelters syndrome and Turners syndrome.
Extra chromosomal inheritance, maternal effect, chloroplast and mitochondrial genetic system. Population genetics-gene and genotype frequency, Hardy-Weinberg equilibrium.
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