Ph. D. (Life Science)-National Institute of Immunology, New Delhi
M.Sc. Biomedical Science- University of Delhi, Delhi
B. Sc. (hons)-Biochemistry-University of Delhi, Delhi
Associate Professor- IIS (deemed to be University), Jaipur, India
Senior Research Scientist- IIS (deemed to be University), Jaipur, India
Scientist- SERB, DST, Govt. of India- IIS (deemed to be University), Jaipur, India
Post doctoral fellow- Clinical Research Institute of Montreal (IRCM), Montreal, Canada
Research Assistant-McGill University, Montreal, Canada
Co-ordinator- DBT PG teaching programme at IIS (deemed to be University), Jaipur
Memeber Secretary-CURIE-CRG- IIS (deemed to be University), Jaipur
Incharge-Central Instrument Facility-IIS (deemed to be University), Jaipur
Incharge- Animal Cell Culture Lab- IIS (deemed to be University), Jaipur
Coordinator- SIRO-DSIR
BOS member of the Department
Targeted drug delivery
Gene silencing
Non- communicable human diseases- Type 2 diabetes mellitus, CPC, heypercholesterolemia
Nanotechnology against microbial infection and contamination
Cell and Molecular Biology
Cell and Molecular Biology
Genetic Engineering
Genomics and Proteomics
Bioprocess Enginnering and Technology
Fermentation Technology
Cell signalling
Animal Cell Culture
Have guided 04 Ph.D. scholars and currently superving/ co-supervising 04 scholars
have guided around 6 M. Sc. students for dissertation
1. M Singhal, L Loveleen, R Manchanda, A Syed, AH Bahkali, LS Wong, S Nimesh, Nidhi Gupta*. Design, synthesis and optimization of silver nanoparticles using Azadirachta indica bark extract and its antibacterial application. Journal of Agriculture and Food Research, 2024, 16, 101088
2. S Jain, MK Sharma, A Syed, AH Bahkali, S Nimesh, Nidhi Gupta*, S Chatterjee Synergistic therapeutic effect of Guggul gum resin on antidiabetic activity of saxagliptin. Journal of Agriculture and Food Research, 2024, 18, 101462
3. P Yadav, S Jain, S Nimesh, Nidhi Gupta, S Chatterjee. Grewia tenax bark extract mediated silver nanoparticles as an antibacterial, antibiofilm and antifungal agent. Advances in Natural Sciences: Nanoscience and Nanotechnology, 2024, 15, 015013 (9pp)
4. P Sharma, P Sinha, Nidhi Gupta. Montmorillonite K10 clay promoted one-pot pseudo-five-component synthesis of 5-cyano-6-(phenylthio)-2-((1-phenylvinyl)imino)-4- aryl(or heteroaryl)-2H-pyran-3-carboxylic acid derivatives and their potential cytotoxic activity. Journal of Chemical Sciences, February 2024, 136 (1)
5. P Yadav, M. Singhal, S Chatterjee, S Nimesh, Nidhi Gupta*. Grewia tenax-Mediated Silver Nanoparticles as Efficient Antibacterial and Antifungal Agents. Nanomaterials and Nanotechnology, 2024: 1-14
6. S Jain, N Yadav, A Kesarwani, P Mathur, S Nimesh, Nidhi Gupta, S Chatterjee. Boosting Vigna radiata growth with kitchen waste-synthesized iron nanoparticles. South African Journal of Botany 2023, 162: 29-40
9. S. Goyal, S. Chatterjee, Nidhi Gupta*. Analysis of Antioxidant Potential of Trigonella foenum-graecum (L.) Extract Against Tumorigenesis. Oncologie, 2021, 23 (1): 89-103
11. S Kumar, E Gupta, Nidhi Gupta, S Kaushik, VK Srivastava, S Kumar, S Mehta, A Jyoti. Functional role of iNOS-Rac2 interaction in neutrophil extracellular traps (NETs) induced cytotoxicity in sepsis. Clinica Chimica Acta, 2020, 513, 43-49
12. N Sharma, RM Kumari, Nidhi Gupta, A Syed, AH Bahkali, S Nimesh. Poly-(Lactic-co-Glycolic) Acid Nanoparticles for Synergistic Delivery of Epirubicin and Paclitaxel to Human Lung Cancer Cells. Molecules, 2020, 25, 4243.
13. A Saxena, P Tiwari, N Wahi, A Soni, RC Bansiwal, A Kumar, B Sharma, P Punjabi, Nidhi Gupta, B Malik, KM Medicherla, P Suravajhala, SK Mathur. Transcriptome profiling reveals association of peripheral adipose tissue pathology with type-2 diabetes in Asian Indians. Adipocyte, 2019 Mar, 20:1-12
14. J Jain#, Nidhi Gupta#, R Mathur……SK Mathur. A Study on Impact of BPA in the Adipose Tissue Dysfunction (Adiposopathy) in Asian Indian Type 2 Diabetes Mellitus Subjects. Indian Journal of Clinical Biochemistry, 2019 DOI: 10.1007/s12291-019-00843-y
15. S Gupta, P Tiwari, Nidhi Gupta……P Mathur. Is Pouch Specific to Colon and Not Ileum? Current Pediatric Reviews, 2019, 15(4):259-264
16. P Tiwari, A Saxena, Nidhi Gupta, KM Medicherla, P Suravajhala, SK Mathur. Systems Genomics of Thigh Adipose Tissue from Asian Indian Type-2 Diabetics Revealed Distinct Protein Interaction Hubs. Frontiers in Genetics, 2019 Jan 8; 9:679
17. G. Arya, R. M. Kumari, R. Pundir, S. Chatterjee, Nidhi Gupta, A. Kumar, R. Chandra, S. Nimesh. Versatile biomedical potential of biosynthesized silver nanoparticles from Acacia nilotica bark. Journal of Applied Biomedicine, 2019, 17:115-124
18. G Arya, RM Kumari, N Sharma, Nidhi Gupta, A Kumar, S Chatterjee, S Nimesh. Catalytic, Antibacterial and Antibiofilm Efficacy of Biosynthesised Silver Nanoparticles Using Prosopis Juliflora Leaf Extract Along with Their Wound Healing Potential. Journal of Photochemistry and Photobiology B: Biology 2019, 190: 50-58
19. G Arya, RM Kumari, N Sharma, S Chatterjee, Nidhi Gupta, A Kumar, S Nimesh. Evaluation of antibiofilm and catalytic activity of biogenic silver nanoparticles synthesized from Acacia nilotica leaf extract. Advance in Natural Sciences: Nanoscience and Nanotechnology 2018
20. S Chatterjee, K Shekawat, Nidhi Gupta*. Bioreduction of toxic hexavalent chromium by novel indigenous microbe Brevibacillus agri isolated from tannery wastewater. International Journal of Environmental Science and Technology, July 2018, 1735-1472
21. S Gupta#, Nidhi Gupta#, P Tiwari#, S Menon, P Mathur, SL Kothari, S Nallapeta, KM Medicherla, P Suravajhala. Lnc-EPB41-Protein Interactions Associated with Congenital Pouch Colon. Biomolecules, 2018 Sep 17; 8(3)
22. SK Mathur, P Tiwari, S Gupta, Nidhi Gupta, S Nimesh, KM Medicherla, P Suravajhala. Genetics of Lipodystrophy: Can It Help in Understanding the Pathophysiology of Metabolic Syndrome? Biomolecules, 2018 Jul 6; 8(3)
23. S Goyal, Nidhi Gupta, A Kumar, S Chatterjee, S Nimesh. Antibacterial, anticancer and antioxidant potential of silver nanoparticles engineered using Trigonella foenum-graecum seed extract. IET Nanobiotechnology 2018,12(4): 526-533
24. G Arya, N Sharma, J Ahmed, Nidhi Gupta, A Kumar, R Chandra, S Nimesh. Degradation of anthropogenic pollutant and organic dyes by biosynthesized silver nano-catalyst from Cicer arietinum leaves. Journal of Photochemistry and Photobiology B: Biology 2017,174 : 90-96
25. G Arya, RM Kumari, Nidhi Gupta, A Kumar, R Chandra, S Nimesh. Green synthesis of silver nanoparticles using Prosopis juliflora bark extract: reaction optimization, antimicrobial and catalytic activities. Artificial Cells, Nanomedicine and Biotechnology 2017 Jul 18:1-9
26. G Arya, AK Malav, Nidhi Gupta, A Kumar, S Nimesh. Biosynthesis and in vitro antimicrobial potential of silver nanoparticles prepared using Dicomatomentosa plant extract. Nanoscience & Nanotechnology- Asia 2017
27. G Arya, N Kumar, Nidhi Gupta, A Kumar, S Nimesh. Antibacterial potential of silver nanoparticles biosynthesized using Canarium ovatum leaves extract. IET Nanobiotechnology 2017, 11 506-511
28. RM Kumari, N Thapa, Nidhi Gupta, A Kumar, S Nimesh. Antibacterial and photocatalytic degradation efficacy of silver nanoparticles biosynthesized using Cordia dichotoma leaves extract. Nanoscience and Nanotechnology2016, 7, 045009 (8pp).
29. Q Ahmed, Nidhi Gupta, A Kumar, S Nimesh; Antibacterial efficacy of silver nanoparticles synthesized employing Terminalia arjuna bark extract. Artificial Cells, Nanomedicine and Biotechnology 2016, 9, 1-9
30. Nidhi Gupta, N Fisaker, MC Asselin, M Lindholm, C Rosenbohm, H Ørum, J Elman, NG Seidah, EM Staarup; A locked nucleic acid antisense oligonucleotide (LNA) silences PCSK9 and enhances LDLR expression in vitro and in vivo. PLoS One 2010,7,5, e10682.
31. P Kumar, V Sood, R Vyas, Nidhi Gupta, AC Banerjea, M Khanna; Potent inhibition of influenza virus replication with novel siRNA-chimeric-ribozyme constructs. Antiviral Research 2010, 87(2):204-12.
32. Nidhi Gupta, AC Banerjea; C-terminal half of HIV-1 Vif C possesses major determinant for APOBEC3G degradation. AIDS. 2009 Jan 2; 23(1): 141-3.
33. Nidhi Gupta, AS Bano, Y Sharma, AC Banerjea; Potent knockdown of the X RNA of hepatitis B by a novel chimeric siRNA-ribozyme construct and modulation of intracellular target RNA by selectively disabled mutants. Oligonucleotides. 2008; Fall 18(3): 225-33.
34. Nidhi Gupta, AS Bano, Y Sharma, V Sood, AC Banerjea; Potent intracellular knock down of Hepatitis B virus X RNA by catalytic hammerhead ribozymes or DNA-enzymes with antisense DNA-oligonucleotides or 10-23 DNA-enzymes that powerfully augment in vitro sequence-specific cleavage activities. The Open Biotechnology Journal. 2008; 2: 1-12.
35. S Roy, Nidhi Gupta, T Mondal, Nithya S, AC Banerjea, S Das. Sequence specific cleavage of Hepatitis C virus by DNA-enzymes: Inhibition of viral RNA translation and replication. Journal of General Virology. 2008; July 89 (Pt 7): 1579-86
36. Nidhi Gupta, V Sood, AS Bano, AC Banerjea; X protein of hepatitis B virus potently activates HIV-1 subtype C LTR promoter: implications of faster spread of HIV-1 subtype C. AIDS. 2007; 21, 1491-92.
37. AS Bano, Nidhi Gupta, V Sood, AC. Banerjea; HIV-1 Vpr Band C RNA cleavage by potent 10-23 DNA-enzymes that also cause reversal of G2 cell cycle arrest mediated by Vpr genes. Oligonucleotides. 2007.
38. AS Bano, Nidhi Gupta, V Sood, AC Banerjea; Vpr from HIV-1subtype B and C exhibits significant differences in their ability transactivate LTR mediated gene expression and also in their ability to promote apoptotic DNA ladder formation. AIDS. 2007; 21(13):1832-4.
39. V Sood, Nidhi Gupta, AC Banerjea; DNA-enzyme mediated cleavage ofHIV-1 Gag RNA is significantly augmented by antisense-DNA molecules targeted tohybridize close to the cleavage site. Oligonucleotides. 2007; 17,113-121.
40. V Sood, Nidhi Gupta, V Shankar, AS Bano, AC Banerjea; Basal RANTES promoter activity differs considerably among different species of monkeys: implications for HIV-1/AIDS progression, AIDS,2007; 21, 116-118.
41. V Sood, H Unwalla, Nidhi Gupta, S Chakraborti, AC Banerjea; Potent knock down of HIV-1 replication by targeting HIV-1 Tat/Rev RNA sequences synergistically with catalytic RNA and DNA. AIDS, 2007; 21, 31-40.
42. H Unwalla, S Chakraborti, V Sood, Nidhi Gupta, AC Banerjea; Potent inhibition of HIV-1 gene expression and TAT-mediated apoptosis in human T cells by novel mono- and multitarget anti-TAT/Rev/Env ribozymes and a general purpose RNA-cleaving DNA-enzyme. Antiviral Research, 2006; 72,134-144. K Sharma, M Gupta, M Pathak, Nidhi Gupta, A Kaul, S Sarangi, R Baweja, Y Singh; Transcriptional control of Mycobacterial embCAB operon by PknH through Regulatory Protein, EmbR, in vivo. Journal of Bacteriology, 2006; 188 (8), 2936-2944.
Review articles
1. A Bharadwaj, P Mathur, S Nimesh, S Chatterjee, Nidhi Gupta*. Meta-analysis of Genetic Factors Responsible for Syndromic Anorectal Malformations in Children. Journal of Neonatalogy, 2024, 38(4):584-594
2. M Singhal, R. Agrawal, Nidhi Gupta*. Impact of PCSK9 mutations on incidences of hypercholesterolemia: A meta-analysis to infer correlation. Meta Gene, 2022, 31, 101019
3. L Khurana, P Chaturvedi, C Sharma, P Bhatnagar, Nidhi Gupta. Toxic effects associated with neonicotinoid exposureon non target organisms: A review. Toxicology International. 2023, 30 (1): 41-50
4. Nidhi Gupta, N Sharma, SK Mathur, R Chandra, S Nimesh. Advancement in nanotechnology-based approaches for the treatment and diagnosis of hypercholesterolemia. Artificial Cells, Nanomedicine and Biotechnology. 2017, 21:1-10.
5. S Goyal, Nidhi Gupta, S Chatterjee, S Nimesh; Natural Plant Extracts as Potential Therapeutic Agents for the Treatment of Cancer. Current Topics in Medicinal Chemistry 2016 17(2): 96 - 106.
6. S Goyal, Nidhi Gupta, S Chatterjee; Investigating therapeutic potential of Trigonella Foenum-graecum L. as our defense mechanism against several human diseases. Journal of Toxicology. 2016; 1250387
7. P Shashi, R Vyas, Nidhi Gupta, B Ahmed, R Chandra, S Nimesh; RNA Interference Technology with emphasis on delivery vehicles-prospects and limitations. Artificial cells Nanomedicine Biotechnology, 2015, July 3: 1-9.
8. S Nimesh, Nidhi Gupta, R Chandra. Cationic Polymer based Nanocarriers for Delivery of Therapeutic Nucleic Acids. Journal of Biomedical Nanotechnology, 2011; 7: 504-520.
9. S Nimesh, Nidhi Gupta, R Chandra. Strategies and Advances in Nanomedicine for Targeted siRNA Delivery. Nanomedicine, 2011; 6: 729-746.
Books/ Monographs Edited
Book Chapters
DST-Rajasthan sponsored project (2025-27)
Nanotechnology based silencing of the expression of Proprotein Convertase Subtilisin/Kexin-9 (PCSK9) for the treatment of Hypercholestrolemia
Women Scientist Scheme-A (WOS-A) (2022)
Project Reference No. DST/WOS-A/LS-290/2019 enitled “The project entitled Investigation of the correlation of serum Proprotein Convertase Subtilisin Kexin-9 (PCSK9) in Type 2 Diabetes Mellitus patients and Coronary Artery diseases” (thankfully declined).
DBT-Foldscope Research grant (2018-2019)
Department of Biotechnology, Government of India in collaboration with Prakash Labs. Standford (US) has sanctioned project, entitled "To observe the factors responsible for antibiotic resistance in hospital generated water borne pathogenic microbes".
Young Scientist Project (2013- 2016)
Science & Engineering Research Board (SERB), Department of Science and Technology (SERC Fast Track Proposals for Young Scientists Scheme), Government of India, entitled, “Genetic analysis of proprotein convertase subtilisin/kexin-9 (PCSK9) to decipher its correlation with cardiovascular diseases in India”
Member of Metabolism and Molecular Research Society