BIOPROCESS TECHNOLOGY AND IPR

Paper Code:

BTE 423

Credits:

Contact Hours:

100

Objective:

Course Outcomes (COs):

Course Outcomes

Learning and teaching strategies

Assessment Strategies

On completion of this course, the learner will

CO 93: Develop designing and working of various fermenters and bioprocess parameters from market point of view

CO 94: Evaluate isolation and screening strategies of microorganisms from industrial context and analyze medium formulation

CO 95: Formulate recovery operations together with the fundamental principles for basic methods in production technique for bio-based products.

CO 96: Evaluate rationale for and against IPR and especially patents

CO 97: Acquaint with broad outline of patent, regulations and protection of products derived from research and issues related to application and obtaining patents

Class lectures

Seminars

Tutorials

Group discussions and Workshops

Question preparation

Class test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Presentation

17.00

Unit I:

Introduction of bioprocess engineering

Bioreactors: Conventional and Specialized bioreactors (pulsed, fluidized, photo bioreactors), Types of fermentation processes: batch, fed batch and continuous cultures kinetics. Process control parameters (pH, temperature, oxygen, foam) Elemental balance equations; metabolic coupling – ATP and NAD+; yield coefficients; unstructured models of microbial growth; structured models of microbial growth

15.00

Unit II:

Isolation and screening strategies of industrially important cultures

Media formulation and sterilization, Isolation of cultures, screening for activities, inoculum preparation. Culture preservation, maintenance, Strain improvement, Techniques of Enzyme immobilization.

13.00

Unit III:

Downstream processing

Introduction, Removal of microbial cells and solid matter, foam separation, cell disruption, precipitation, filtration, centrifugation, liquid-liquid extraction, chromatography, membrane process, Drying and crystallization

15.00

Unit IV:

Introduction to IPR

Introduction to intellectual property; types of IP: patents, trademarks, copyright & related rights, industrial design, traditional knowledge, geographical indications, protection of new GMOs; International framework for the protection of IP; IP as a factor in R&D; IPs of relevance to biotechnology and few case studies; introduction to history of GATT, WTO, WIPO and TRIPS; plant variety protection and farmers rights act; concept of ‘prior art’: invention in context of “prior art”; patent databases - country-wise patent searches (USPTO, EPO, India); analysis and report formation.

15.00

Unit V:

Patenting

Basics of patents: types of patents; Indian Patent Act 1970; recent amendments; WIPO Treaties; Budapest Treaty; Patent Cooperation Treaty (PCT) and implications; procedure for filing a PCT application; role of a Country Patent Office; filing of a patent application; precautions before patenting-disclosure/non-disclosure - patent application- forms and guidelines including those of National Bio-diversity Authority (NBA) and other regulatory bodies, fee structure, time frames; types of patent applications: provisional and complete specifications; PCT and conventional patent applications; international patenting-requirement, procedures and costs; financial assistance for patenting; introduction to existing schemes; publication of patents-gazette of India, status in Europe and US; patent infringement- meaning, scope, litigation, case studies and examples; commercialization of patented innovations; licensing – outright sale, licensing, royalty; patenting by research students and scientists-university/organizational rules in India and abroad, collaborative research - backward and forward IP; benefit/credit sharing among parties/community, commercial (financial) and non-commercial incentives.

ESSENTIAL READINGS:

ESSENTIAL READINGS:

Stanbury, P. F., & Whitaker, A. (2010). Principles of Fermentation Technology. Oxford: Pergamon Press.
El-Mansi, M., & Bryce, C. F. (2007). Fermentation Microbiology and Biotechnology. Boca Raton: CRC/Taylor & Francis.
Michael L. Shuler, FikretKargi, Bioprocess Engineering – Basic Concepts, 2nd Ed., Pearson Education India, 2015
Ganguli, P. (2001). Intellectual Property Rights: Unleashing the Knowledge Economy. New Delhi: Tata McGraw-Hill Pub.
Complete Reference to Intellectual Property Rights Laws. (2007). Snow White Publication Oct. 4. Kuhse, H. (2010). Bioethics: an Anthology. Malden, MA: Blackwell.
Prateek Kasliwal, (2009), Intellectual Property Rights, College Book Centre, 1st edition.
VK Ahuja, (2009), Intellectual Property Rights in India, Lexis Nexis Publication, 1st edition (Vol.1 and 2).
P Narayanan, (2001), Intellectual Property Law, Eastern Law House, 3rd edition.
Latha R Nair & Rajendra Kumar, (2005), Geographical Indications: A Search for Identity, Lexis Nexis Publication, 1st edition.
VK Ahuja, (2007), Law of Copyright and Neighbouring Rights: National and International Perspectives, Lexis Nexis Publication.
Lionel Bently and Brad Sherman, (2004), Intellectual property law, Oxford Publication.
Kailasam and Vedaraman, (2009), Law of Trade Marks and Geographical Indications, Lexis Nexis Publication, 2nd edition.
Feroz Ali Khader, (2007), The Law of Patents-With a Special Focus on Pharmaceuticals in India, Lexis Nexis Publication, 1st edition.
N R Subbaram, (2007), Patent Law Practices and Procedures, Lexis Nexis Publication, 2nd edition.

SUGGESTED READINGS:

Roger G. Harrison, Paul W. Todd, Scott R. Rudge, Demetri P. Petrides, Bioseparations Science and Engineering, 2nd Ed., Oxford University Press, 2003.
Pauline M. Doran, Bioprocess Engineering Principles, 2nd Ed., Academic Press, 2012
James Bailey, David Ollis, Biochemical Engineering Fundamentals, 2nd Ed., McGraw Hill Education, 2017

REFERENCES:

e RESOURCES:

https://library.wit.edu/guides/biological-engineering/bioprocess-engineering

WIPO Magazine: https://www.wipo.int/wipo_magazine/en/